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Editors   Breakthrough: Human Hearts Can Grow New Cells   4/20/2009 11:50:00 AM    Comment now Breakthrough: Human Hearts Can Grow New Cells
In the April 3 issue of the journal Science, a team from University of Toronto and University of Wisconsin-Madison announced their discovery that heart cells regenerate throughout a human lifetime, with a 1 percent annual turnover rate at age 25, falling to a 0.45 percent turnover rate at age 75.

Therefore, the human heart must have it's own stem cells.
Editors   Horse Stem Cell Technique to be Tested on Humans   4/16/2009 9:00:00 AM    Comment now Horse Stem Cell Technique to be Tested on Humans
It's rare for veterinary medicine to lead human medicine, but race horses are a different breed. A stem cell technique that has been used to quickly repair the tendons of race horses will be tried in humans for the first time.

British biotech firm MedCell Bioscience Ltd said on Wednesday it would start clinical tests within 12 months to extract Mesenchymal adult stem cells from a patien...
Editors   SHOCK: Obama Signs Bill Banning Federal Funding of Embryonic Stem Cells   3/13/2009 1:20:00 PM    Comment now SHOCK: Obama Signs Bill Banning Federal Funding of Embryonic Stem Cells
President Obama signed H.R. 1105, the “Omnibus Appropriations Act, 2009 (aka omnibus appropriations bill) on Wednesday which included a hidden provision that explicitly bans federal funding of any "research in which a human embryo or embryos are destroyed, discarded, or knowingly subjected to risk of injury or death."

This bill is counter to the claims of Obama made just Monday where "sc...
Editors   Executive Order: REMOVING BARRIERS TO RESPONSIBLE SCIENTIFIC RESEARCH INVOLVING HUMAN STEM CELLS   3/9/2009 1:00:00 PM    Comment now Executive Order: REMOVING BARRIERS TO RESPONSIBLE SCIENTIFIC RESEARCH INVOLVING HUMAN STEM CELLS
The text of President Obama's Executive Order lifting restrictions on Federal funding of embryonic stem cells.
Editors   Speech: Obama Authorizes Federal Funding for Embryonic Stem Cell Research March 9 2009   3/9/2009 11:45:00 AM    Comment now Speech: Obama Authorizes Federal Funding for Embryonic Stem Cell Research March 9 2009
President Obama authorizes Federal funding of embryonic stem cell research by signing an Executive Order.
Editors   Policy: Obama Signs Executive Order Authorizing Federal Funding of Embryonic Stem Cell Research   3/9/2009 11:45:00 AM    Comment now Policy: Obama Signs Executive Order Authorizing Federal Funding of Embryonic Stem Cell Research
President Obama signed an Executive Order authorizing Federal funding for embryonic stem cell research - overturning President Bush's ban on such funding.

Stay tuned for the details of the order.
Editors   Video: Facts - What are Cancer Stem Cells?   3/8/2009 9:20:00 PM    Comment now Video: Facts - What are Cancer Stem Cells?
Video about cancer stem cells by Dr. Mike Magee of Health Politics.

Stem cells have these properties, they can: self-renew, multiply, and proliferate extensively. We normally think about stem cells as being good and having healing properties.

But if those properties are subverted by the body, they may become "evil" stem cells and may cause cancer. (There is some dispute at this...
Editors   FLASH: Policy: Obama to Sign Embryonic Stem Cell Executive Order Monday   3/6/2009 4:06:00 PM    Comment now FLASH: Policy: Obama to Sign Embryonic Stem Cell Executive Order Monday
President Obama will sign an executive order Monday authorizing Federal funds to be used in embryonic stem cell research.

This was widely expected. However, it is ironic this funding will be available just as embryonic stem cells may not be needed with the recent advances in 'artificial' embryonic stem cells (aka iPS or induced pluripotent cells).
Editors   Breakthrough: Induced Stem Cells Now Made Cancer Free   3/6/2009 9:30:00 AM    Comment now Breakthrough: Induced Stem Cells Now Made Cancer Free
Since 2007, scientists have been able to reprogram adult stem cells, like skin, into (artificial) embryonic stem cells by using viruses or genes. However, these inserted viruses or genes had the potential to cause cancer or other problems.

Dr. Rudolf Jaenisch' stem cell research team at MIT and the Whitehead Institute for Biomedical Research in Cambridge, Mass., recently found a way to ...
Editors   Deal: Stem Cells Inc. Diversifies with Embryonic Stem Cell Acquisition   3/6/2009 8:40:00 AM    Comment now Deal: Stem Cells Inc. Diversifies with Embryonic Stem Cell Acquisition
US based Stem Cells, Inc. (StemCells) acquires UK and Australia based Stem Cell Sciences plc in $5 million stock and cash deal.

This is StemCells's gambit to diversify from being solely an adult stem cell business into being a global provider of embryonic stem cells, induced stem cells (artificial embryonic), and adult stem cells.
Editors   Policy: Are Embryonic Stem Cells Obsolete?   3/5/2009 9:50:00 AM    Comment now Policy: Are Embryonic Stem Cells Obsolete?
With the recent advances in reprogramming adult stem cells to mimic embryonic stem cells, and their increased survival rate in patients, has the need for embryonic stem cell research ended?

Bernadine Healy, M.D., the former head of the National Institutes of Health, and the American Red Cross, states her case.
Editors   Breakthrough: Australian Scientists Regrow Mice Muscle Tissue from Adult Stem Cells   3/4/2009 10:05:00 AM    Comment now Breakthrough: Australian Scientists Regrow Mice Muscle Tissue from Adult Stem Cells
Australian scientists have become the first in the world to use adult stem cells (from a donor) to regrow damaged muscle tissue (in mice), offering hope to sufferers of muscular dystrophy.

They overcame the problem of getting the donor cells to survive for more than an hour.
Editors   Breakthrough: UCLA Team Creates Nerve Cells From Skin - Bypassing Embryos   2/25/2009 10:27:00 AM    Comment now Breakthrough: UCLA Team Creates Nerve Cells From Skin - Bypassing Embryos
A team from the University of California Los Angeles led by William Lowry, created the first motor neurons from artificial embryonic stem cells, called induced pluripotent stem cells, or iPS cells, which were in turn created from ordinary skin cells.

This has huge implications for the debate over the use of and need for embryonic stem cells.

Their next step is to attach their neur...
Editors   Human Trials: Man Cured of Multiple Sclerosis Using Adult Stem Cells   2/23/2009 11:40:00 AM    Comment now Human Trials: Man Cured of Multiple Sclerosis Using Adult Stem Cells
A Northwestern University clinical trial using adult stem cells 'cures' Edwin McClure, a Virginia Commonwealth University advertising graduate student with multiple sclerosis.

Stem cells were removed from his bone marrow and grown in a lab. His existing cells were destroyed by chemotherapy, then replaced by the new ones via injection.

His symptoms have since disappeared.
Editors   Human Trials: World's First Adult Stem Cells from Heart Tissue to Repair Heart   2/11/2009 3:00:00 PM    Comment now Human Trials: World's First Adult Stem Cells from Heart Tissue to Repair Heart
The world's first FDA-approved clinical trial using adult stem cells derived from heart tissue to treat heart disease will be conducted by a team of University of Louisville doctors at Jewish Hospital.

Bypass patients will have some tissue re...
Editors   Treatment: Police Dog Healed with Own Stem Cells   2/10/2009 11:06:48 AM    Comment now Treatment: Police Dog Healed with Own Stem Cells
Cris, a Fremont PD police dog was given stem cell therapy to repair a torn muscle. Eleven weeks after Dr. Gary Brown, a veterinary surgeon, extracted the dog's own fat cells and injected them into Cris, the cells look like normal muscle.
Editors   Tourism: Costa Rica Clinic Hopes for Quadriplegic   2/10/2009 10:00:00 AM    Comment now Tourism: Costa Rica Clinic Hopes for Quadriplegic
Thousands of people travel to clinics around the world, from China to Mexico to Ukraine, in the hope of being cured for Alzheimer's, Multiple Sclerosis, nerve damage and more.

A quadriplegic from Arlington, Texas spent $20,000 on stem cell injections at the Institute for Cellular Medicine in San Jose, Costa Rica in an effort to walk again.
Editors   Further Advance in Artificial Stem Cells - Blood Platelets Created   2/9/2009 12:28:00 PM    1 comment
Kyoto University's Shinya Yamanaka and University of Tokyo's Naoya Takayama were the first in the world to generate induced pluripotent stem cells (iPS) cells (think artificial embryonic stem cells) using skin cells from mice in 2006, then in humans in November 2007. They have now proceeded to the next step by creating blood platelets using these cells.

Editors   Video: What are Induced Pluripotent Stem Cells? June 25 2008   2/9/2009 6:00:00 AM    Comment now Video: What are Induced Pluripotent Stem Cells? June 25 2008
Induced Pluripotent Stem Cells were developed in 2007 by Shinya Yamanaka of Kyoto University. Dr. Yamanaka and his team derived the cells by adding proteins that reprogram adults cells, reverting them to their embryonic state. "These new cells are expected to live for a very long time while retaining the ability to form all of the different tissues found in a human body.

iPSC cells do no...
Editors   Breakthrough: Australia Creates its First 'Artificial' Embryonic Stem Cells from Skin Cells   2/2/2009 9:30:00 AM    Comment now Breakthrough: Australia Creates its First 'Artificial' Embryonic Stem Cells from Skin Cells
Australian scientists have produced their nation's first human induced pluripotent stem (iPS) cells - cells that act like embryonic stem cells but instead were made from adult skin cells.

They now join the club of nations, Japan and the United States, that can skirt around the ethical issues of obtaining stem cells from embryos.
Editors   Human Trials: Adult Stem Cell Therapy Stabilizes Multiple Sclerosis Patients   2/1/2009 1:00:00 PM    Comment now Human Trials: Adult Stem Cell Therapy Stabilizes Multiple Sclerosis Patients
Northwestern University researchers used stem cells from a patient's own body (adult stem cells) in 21 patients, 11 women and 10 men, with relapsing-remitting MS who had not responded to treatment.

After three years, 17 patients improved. This is very hopeful since, most people with MS , after the 10 year mark, usually develop a secondary-progressive form of the disease, and experience ...
Editors   Breakthrough: World's First Extinct Animal Brought Back to Life - Through Cloning   2/1/2009 11:30:00 AM    Comment now Breakthrough: World's First Extinct Animal Brought Back to Life - Through Cloning
For the first time ever, an extinct animal has been resurrected through cloning.

A wild mountain goat, called a Pyrenean ibex, died out in the year 2000 in northern Spain. Skin samples were saved from the animal and kept frozen in liquid nitrogen.
Editors   Breakthrough: World's First Cloned Puppies from Fat Stem Cells   1/30/2009 11:30:00 AM    Comment now Breakthrough: World's First Cloned Puppies from Fat Stem Cells
RNL Bio, a South Korean biotech company, in conjunction with Seoul National University, created the world's first cloned puppies (named Stem and Magic) from fat stem cells.

Other animals have been cloned using stem cells, but this is the first for a dog.
Editors   Video: How Stem Cells Develop From Embryonic to Adult Cells   1/26/2009 9:00:00 AM    Comment now Video: How Stem Cells Develop From Embryonic to Adult Cells
Intermediate level 8 minute video explains how stem cells develop from embryo to adult cells.

Has beautiful graphics showing self replenishing cells in the intestines (similar to the ones in the skin, hair, and bones).

Explains how the nervous system, pancreas and the heart all regenerate too poorly to restore themselves after serious injury or degenerative disease.
Editors   Video: What makes a Stem Cell Pitch from Google TechTalk July 31, 2007   1/26/2009 6:00:00 AM    Comment now Video: What makes a Stem Cell Pitch from Google TechTalk July 31, 2007
Presentation at Google TechTalks by Daniel Kraft, MD of Stanford School of Medicine. 51 minute PowerPoint pitch.

Overview:

  • What Makes a Stem Cell
  • Adult vs. Embryonic Stem Cells (ESC)
  • Applications of Adult Stem Cells
  • Qhere do stem cells come from?
  • What are cancer stem cells
  • Challenges of ESC

Editors   Breakthrough: Origin of Blood Stem Cells Discovered   1/18/2009 11:50:00 AM    Comment now Breakthrough: Origin of Blood Stem Cells Discovered
The timeline of development of blood (hematopoietic) stem cells (HSCs) from the embryo to bone marrow has been proven in mice by a research team led by Nancy Speck, PhD, Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.

HSCs are found in the bone marrow of adults and generate all of the blood cell types in the body.

During developmen...
Editors   FDA: Possibly First Ever Stem Cell Drug for FDA Approval   1/17/2009 11:31:00 AM    Comment now FDA: Possibly First Ever Stem Cell Drug for FDA Approval
Osiris Therapeutics (NASDAQ:OSIR) expects to have the first ever stem cell drug for FDA approval.

Prochymal would treat Graft vs. host disease, assisting bone marrow transplant patients to prevent the implanted marrow's immune cells from attacking the body.
Editors   Human Trials: California's First Stem Cell therapy to Repair Human Heart   1/17/2009 9:31:00 AM    Comment now Human Trials: California's First Stem Cell therapy to Repair Human Heart
California's first stem cell therapy study will repair human hearts.

45 patients will be injected with millions of adult stem cells that will grow and replace damaged heart cells.
Editors   Breakthrough: Stem Cells Create New Windpipe   12/22/2008 3:30:00 PM    Comment now Breakthrough: Stem Cells Create New Windpipe
In June 2008, Claudia Castillo has first-ever windpipe surgery at the Hospital Clinic in Barcelona, Spain.

Her stem cells were used to create cartilage, tissue cells to cover her new windpipe.

Making Stem Cells Understandable

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