Breakthrough: Human Hearts Can Grow New Cells |
Hearts have stem cells |
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Editors published 4/20/2009 11:50:00 AM
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In the April 3 issue of the journal Science, a team from University of Toronto and University of Wisconsin-Madison announced their discovery that heart cells regenerate throughout a human lifetime, with a 1 percent annual turnover rate at age 25, falling to a 0.45 percent turnover rate at age 75.
Therefore, the human heart must have it's own stem cells.
Scientists had long thought organs such as the heart, brain and pancreas were unable to regenerate after being formed, though they obviously grow in size. They could create new cells but lacked stores of heart- or brain-specific stem cells, the thinking went. This theory was largely based on the fact that it is very difficult to recover lost function if those organs are damaged by illness or injury.
The researchers now postulate that the heart does in fact have stem cells, and that these may be harnessed for therapeutic treatments.
For instance, the finding could help doctors design treatments for the damage caused by heart attacks, which was previously thought to be irreversible.
Overall, it is starting to look like the body has a lot more potential for regeneration than doctors had suspected.
This discovery should lead to further breakthroughs in developing adult stem cells from the heart.
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