Editors: Policy: Are Embryonic Stem Cells Obsolete?

Editors: Policy: Are Embryonic Stem Cells Obsolete?

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Policy: Are Embryonic Stem Cells Obsolete?

Editors published 3/5/2009 9:50:00 AM
Source: Why Embryonic Stem Cells Are Obsolete Bernadine Healy , US News
With the recent advances in reprogramming adult stem cells to mimic embryonic stem cells, and their increased survival rate in patients, has the need for embryonic stem cell research ended?

Bernadine Healy, M.D., the former head of the National Institutes of Health, and the American Red Cross, states her case.

Even as the future of embryonic stem cells has dimmed, adult stem cell research has scored major wins evident just in the past few months. These advances involve human stem cells that are not derived from human embryos. In fact, adult stem cells, which occur in small quantities in organs throughout the body for natural growth and repair, have become stars despite great skepticism early on. Though this is a more difficult task, scientists have learned to coax them to mature into many cell types, like brain and heart cells, in the laboratory

To date, most of the stem cell triumphs that the public hears about involve the infusion of adult stem cells. We've just recently seen separate research reports of patients with spinal cord injury and multiple sclerosis benefiting from adult stem cell therapy. These cells have the advantage of being the patient's natural own, and the worst they seem to do after infusion is die off without bringing the hoped-for benefit.

A second kind of stem cell that has triumphed is an entirely new creation called iPS (short for induced pluripotent stem cell), a blockbuster discovery made in late 2007. These cells are created by reprogramming DNA from adult skin. The iPS cells are embryonic-like in that they can turn into any cell in the body—and so bypass the need for embryos or eggs. In late February, scientists reported on iPS cells that had been transformed into mature nerve cells.


Ms. Healy does provide some clarity to the two stem cell bans currently in place.

it's important that Obama and everyone supporting a lifting of the ban be clear with the public on what is involved in this decision; it's more complex than advertised.

The ban Bush became famous for restricted the use of federal research dollars just to adult stem cells and embryonic stem cells already in existence at the time of his executive order. Lifting this ban so that researchers can use frozen embryos that would otherwise be discarded—they've been donated by couples who have had in vitro fertilization treatments—has drawn wide and bipartisan support from Congress. It's an easy lift.

The more ethically charged decision—less understood by the public and one Congress has avoided—involves the ban on creating human embryos in the laboratory solely for research purposes. In fact, President Clinton is the one who balked at allowing scientists to use government money for embryo creation and research on stem cells harvested from such embryos; Bush only affirmed the Clinton ban. The scientific community has been able to attract nonfederal money for such work, and it is going on all the time in stem cell institutes. Scientists want relief from the inconvenience and expense of keeping that work and the money that supports it separate from federal dollars.

Reversing the executive orders of two prior presidents on embryo creation, which even the Congress has been unwilling to tackle, is a far bigger issue than lifting the ban on the use of IVF embryos slated for destruction. Obama stands for transparency, and it's important for him to make sure the public understands his decision, including that all stem cells are not the same or created equally.
Tags: US Policy Adult Stem Cells Breakthrough Embryonic Bush    Share: digg newsvine reddit del.icio.us facebook stumbleupon

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